CUR-IPA
CUR-IPA is a cholinesterase inhibitor, with IC50 of 5.99, 59.30, and 60.66 μM for eAChE (electric eel), hAChE (human), and hBChE (human), respectively. CUR-IPA can scavenge free radicals and has antioxidant activity. CUR-IPA can be used in the research of cognitive dysfunction[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Smiles
COC1=CC(/C=C/C(CC(/C=C/C2=CC=C(C(OC)=C2)OC(CCC3=CNC4=C3C=CC=C4)=O)=O)=O)=CC=C1OC(CCC5=CNC6=C5C=CC=C6)=O
Molecular Formula
C43H38N2O8
Molecular Weight
710.77
References & Citations
[1]Sidhambaram J, et al. Esterified Indole-3-propionic Acid: A Novel Inhibitor against Cholinesterase Identified through Experimental and Computational Approaches. ACS Omega. 2025 Mar 1;10 (9) :9073-9087.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
Curated Selection
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