TSO-13
TSO-13 is the inhibitor for the main cysteine protease of Trypanosoma cruzi Cruzipain with an IC50 of 2.2 μM. TSO-13 inhibits T. cruzi in Vero cell with an IC50 of 1.9 μM[1].
Product Specifications
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=S(SC[C@H](N1C=C(N=N1)C(C2CCCCC2)NCC3=CC4=C(OCO4)C=C3)CC5=CC=CC=C5)(C6=CC=CC=C6)=O
Molecular Formula
C32H36N4O4S2
Molecular Weight
604.78
References & Citations
[1]Cerutti J P, et al. Thiosulfonate-Based Targeted Covalent Cruzipain Inhibitors with Enhanced Bioactivity Translation for Antichagasic Therapy[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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