TSO-13
TSO-13 is the inhibitor for the main cysteine protease of Trypanosoma cruzi Cruzipain with an IC50 of 2.2 μM. TSO-13 inhibits T. cruzi in Vero cell with an IC50 of 1.9 μM[1].
Product Specifications
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=S(SC[C@H](N1C=C(N=N1)C(C2CCCCC2)NCC3=CC4=C(OCO4)C=C3)CC5=CC=CC=C5)(C6=CC=CC=C6)=O
Molecular Formula
C32H36N4O4S2
Molecular Weight
604.78
References & Citations
[1]Cerutti J P, et al. Thiosulfonate-Based Targeted Covalent Cruzipain Inhibitors with Enhanced Bioactivity Translation for Antichagasic Therapy[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items