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TSO-13

TSO-13 is the inhibitor for the main cysteine protease of Trypanosoma cruzi Cruzipain with an IC50 of 2.2 μM. TSO-13 inhibits T. cruzi in Vero cell with an IC50 of 1.9 μM[1].

Product Specifications

UNSPSC

12352005

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=S(SC[C@H](N1C=C(N=N1)C(C2CCCCC2)NCC3=CC4=C(OCO4)C=C3)CC5=CC=CC=C5)(C6=CC=CC=C6)=O

Molecular Formula

C32H36N4O4S2

Molecular Weight

604.78

References & Citations

[1]Cerutti J P, et al. Thiosulfonate-Based Targeted Covalent Cruzipain Inhibitors with Enhanced Bioactivity Translation for Antichagasic Therapy[J]. ACS Medicinal Chemistry Letters, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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