BI-1915
BI-1915, a chemical probe, is the selective inhibitor for Cathepsin S with an IC50 of 17 nM. BI-1915 can be used in research of autoimmune diseases[1].
Product Specifications
CAS Number
752237-67-5
UNSPSC
12352005
Target
Cathepsin
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(N1CCOCC1)N[C@@H](CCC(C)(C)CC)C(NC2(CCN(CC2)C)C#N)=O
Molecular Formula
C21H37N5O3
Molecular Weight
407.55
References & Citations
[1]Moss N, et al., Exploration of cathepsin S inhibitors characterized by a triazole P1-P2 amide replacement. Bioorg Med Chem Lett. 2012 Dec 1;22 (23) :7189-93.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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