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BI-1915

BI-1915, a chemical probe, is the selective inhibitor for Cathepsin S with an IC50 of 17 nM. BI-1915 can be used in research of autoimmune diseases[1].

Product Specifications

CAS Number

752237-67-5

UNSPSC

12352005

Target

Cathepsin

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Smiles

O=C(N1CCOCC1)N[C@@H](CCC(C)(C)CC)C(NC2(CCN(CC2)C)C#N)=O

Molecular Formula

C21H37N5O3

Molecular Weight

407.55

References & Citations

[1]Moss N, et al., Exploration of cathepsin S inhibitors characterized by a triazole P1-P2 amide replacement. Bioorg Med Chem Lett. 2012 Dec 1;22 (23) :7189-93.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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