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MRK-990

MRK-990, a chemical probe, is the inhibitor for PRMT that inhibits PRMT5 and PRMT9 with IC50 of 30 nM and 10 nM[1].

Product Specifications

UNSPSC

12352005

Target

Histone Methyltransferase

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O[C@@H]1[C@H](O)[C@@H](CSCCCCNCC2=CC=CN=C2C(C)(C)C)O[C@H]1N3C=C(C)C4=C3N=CN=C4N

Molecular Formula

C26H38N6O3S

Molecular Weight

514.68

References & Citations

[1]Sbardella G, et al., Chapter 11: Inhibiting Arginine Methylation

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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