MRK-990
MRK-990, a chemical probe, is the inhibitor for PRMT that inhibits PRMT5 and PRMT9 with IC50 of 30 nM and 10 nM[1].
Product Specifications
UNSPSC
12352005
Target
Histone Methyltransferase
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O[C@@H]1[C@H](O)[C@@H](CSCCCCNCC2=CC=CN=C2C(C)(C)C)O[C@H]1N3C=C(C)C4=C3N=CN=C4N
Molecular Formula
C26H38N6O3S
Molecular Weight
514.68
References & Citations
[1]Sbardella G, et al., Chapter 11: Inhibiting Arginine Methylation
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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