E3 Ligase Ligand-linker Conjugate 172

E3 Ligase Ligand-linker Conjugate 172 is the conjugate composed of an E3 ligase ligand and a linker, and can be used for synthesis of PROTAC degrader FF2039 (HY-172159) [1].

Product Specifications

UNSPSC

12352211

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Cancer

Smiles

O=C(O)CCCCCCCCCCCN(C(C1=CC=C(Cl)C(Cl)=C1)C(NCC2=CC=CC=C2)=O)C(CCl)=O

Molecular Formula

C29H37Cl3N2O4

Molecular Weight

583.97

References & Citations

[1]Feller F, et al., Replacing a Cereblon Ligand by a DDB1 and CUL4 Associated Factor 11 (DCAF11) Recruiter Converts a Selective Histone Deacetylase 6 PROTAC into a pan-degrader. ChemMedChem. 2025 Feb 20:e202500035.