DNMT-IN-4
DNMT-IN-4 (Compound 4d) is a DNMT inhibitor with an IC50 of 5.78 μM. DNMT-IN-4 can induce apoptosis and has anticancer activity[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; DNA Methyltransferase
Related Pathways
Apoptosis; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
ClC(C=CC=C1)=C1C(N2CCC3=C(C2)C=CS3)C(S4)=NN=C4NC5CCCCC5
Molecular Formula
C22H25ClN4S2
Molecular Weight
445.04
References & Citations
[1]Karakuş, S., et al. Synthesis and Apoptotic Effects of DNMT Inhibition Targeted Novel Hybrid Molecules Bearing Thiadiazole and Clopidogrel for Cancer Treatment. Polycyclic Aromatic Compounds, 1–24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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