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DNMT-IN-4

DNMT-IN-4 (Compound 4d) is a DNMT inhibitor with an IC50 of 5.78 μM. DNMT-IN-4 can induce apoptosis and has anticancer activity[1].

Product Specifications

UNSPSC

12352005

Target

Apoptosis; DNA Methyltransferase

Related Pathways

Apoptosis; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

ClC(C=CC=C1)=C1C(N2CCC3=C(C2)C=CS3)C(S4)=NN=C4NC5CCCCC5

Molecular Formula

C22H25ClN4S2

Molecular Weight

445.04

References & Citations

[1]Karakuş, S., et al. Synthesis and Apoptotic Effects of DNMT Inhibition Targeted Novel Hybrid Molecules Bearing Thiadiazole and Clopidogrel for Cancer Treatment. Polycyclic Aromatic Compounds, 1–24.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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