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HCAIX/XII-IN-14

HCAIX/XII-IN-14 (Compound 1i) is an hCAIX/XII inhibitor, with Ki values of hCAII, hCAIX, and hCAXII for 9.4 nM, 5.6 nM, and 6.3 nM, respectively[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

NS(=O)(C1=CC=C(C=C1)NC(CO/N=C/C2=CC=C(C=C2)C(F)(F)F)=O)=O

Molecular Formula

C16H14F3N3O4S

Molecular Weight

401.36

References & Citations

[1]Nencetti S, et al. A series of benzensulfonamide derivatives as new potent carbonic anhydrase IX and XII inhibitors. Future Med Chem. 2025 Feb;17 (3) :271-285.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CA II; CA IX; CA XII

Curated Selection

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