RA-PR058
RA-PR058 is an orally active Ramalin derivative with blood-brain barrier permeability, exhibiting multi-target regulatory effects and favorable pharmacokinetic properties. RA-PR058 demonstrates potential as a multi-target modulator for Alzheimer's disease by reducing the expression of BACE1, tau protein hyperphosphorylation, and anxiety-like behaviors[1].
Product Specifications
UNSPSC
12352005
Target
Beta-secretase; Tau Protein
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(NNC1=CC=CC=C1F)CC[C@H](N)C(F)F.Cl
Molecular Formula
C11H15ClF3N3O
Molecular Weight
297.70
References & Citations
[1]Cho Y, et al. RA-PR058, a novel ramalin derivative, reduces BACE1 expression and phosphorylation of tau in Alzheimer's disease mouse models. Anim Cells Syst (Seoul) . 2025 Feb 7;29 (1) :122-134.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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