CYP17A1-IN-1
CYP17A1-IN-1 (Compound 14) is the inhibitor for CYP17A1 with an IC50 of 26 nM. CYP17A1-IN-1 exhibits cytotoxicity in androgen-sensitive prostate cancer cell LNCaP, inhibits the migration of cell DU-145[1].
Product Specifications
UNSPSC
12352005
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
C12=C(NC=C2)C=CC(C3=CC=CC(C4=CC=NC=C4)=C3)=C1
Molecular Formula
C19H14N2
Molecular Weight
270.33
References & Citations
[1]Wróbel TM, et al., Pyridine indole hybrids as novel potent CYP17A1 inhibitors. J Enzyme Inhib Med Chem. 2025 Dec;40 (1) :2463014.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CYP17
Curated Selection
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