PPARγ-IN-5
PPARγ-IN-5 (Compound A3) is the inhibitor for PPARγ. PPARγ-IN-5 inhibits lipid accumulation in hepatocytes without significant cytotoxicity in HepG2 cell (400 µM) . PPARγ-IN-5 can be used in research of non-alcoholic fatty liver disease[1].
Product Specifications
CAS Number
3038323-12-2
UNSPSC
12352005
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Smiles
O=C(O)/C=C/C1=CC=C(OCCOC(C(C)(OC2=CC=C(Cl)C=C2)C)=O)C(OC)=C1
Molecular Formula
C22H23ClO7
Molecular Weight
434.87
References & Citations
[1]Liu YY, et al., Design, synthesis, and inhibition of novel ferulic acid derivatives on free fatty acid induced cellular lipid accumulation. J Asian Nat Prod Res. 2025 Feb 23:1-16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PPARγ
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