PPO-IN-17

PPO-IN-17 (Compound 6R) is the inhibitor protoporphyrinogen IX oxidase (PPO) that inhibits Nicotiana tobacco PPO (NtPPO) with Ki of 30.34 nM. PPO-IN-17 exhibits herbicidal activity that inhibits barnyardgrass (E. crus-galli), foxtail grass (D. sanguinalis), alfalfa (M. sativa) and Canada cocklebur (C. canadensis) (>95% inhibition rate at a concentration of 37.5 g/hm2) . PPO-IN-17 exhibits no toxicity on rice (at a concentration of 75 g/hm2) or on honeybees (at a concentration of 6400 mg/kg) [1].

Product Specifications

UNSPSC

12352005

Target

Herbicide; Protoporphyrinogen IX oxidase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Smiles

O=C(N(C1=CC(OC(C)C(O/N=C(C2=CC=CC=C2F)\C)=O)=C(Cl)C=C1F)C(N3C)=O)N(C)C3=S

Molecular Formula

C22H19ClF2N4O5S

Molecular Weight

524.92

References & Citations

[1]Luo D, et al., Design, synthesis, and biological evaluation of oxime ether derivatives containing 1,5-dimethyl-6-thioxo-1,3,5-triazinane-2,4-dione as protoporphyrinogen IX oxidase inhibitors. Pest Manag Sci. 2025 Feb 13.