Naltrindole 5′-isothiocyanate
Naltrindole 5′-isothiocyanate (5'-NTII) is a non-selective delta opioid receptor antagonist that can antagonize the analgesic effects induced by DSLET without affecting the analgesic effects induced by DPDPE (HY-P1334).
Product Specifications
CAS Number
126876-64-0
Product Name Alternative
5'-NTII
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O[C@@]12[C@@]([C@](O3)([H])C(NC4=CC=C5N=C=S)=C(C4=C5)C2)(CC6)C(C3=C7O)=C(C=C7)C[C@@]1([H])N6CC8CC8
Molecular Formula
C27H25N3O3S
Molecular Weight
471.57
References & Citations
[1]S Chakrabarti, et al. Differential antagonism by naltrindole-5'-isothiocyanate on [3H]DSLET and [3H]DPDPE binding to striatal slices of mice. Life Sci. 1993;53 (23) :1761-5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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