Naltrindole 5′-isothiocyanate

Naltrindole 5′-isothiocyanate (5'-NTII) is a non-selective delta opioid receptor antagonist that can antagonize the analgesic effects induced by DSLET (HY-P1332) without affecting the analgesic effects induced by DPDPE (HY-P1334) [1].

Product Specifications

CAS Number

[126876-64-0]

Product Name Alternative

5'-NTII

UNSPSC

12352005

Target

Opioid Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Smiles

O[C@@]12[C@@]([C@](O3)([H])C(NC4=CC=C5N=C=S)=C(C4=C5)C2)(CC6)C(C3=C7O)=C(C=C7)C[C@@]1([H])N6CC8CC8

Molecular Formula

C27H25N3O3S

Molecular Weight

471.57

References & Citations

[1]S Chakrabarti, et al. Differential antagonism by naltrindole-5'-isothiocyanate on [3H]DSLET and [3H]DPDPE binding to striatal slices of mice. Life Sci. 1993;53 (23) :1761-5.