Itaconic acid prodrug-1
Itaconic acid prodrug-1 (Compound P2) is an orally active prodrug of Itaconic acid that efficiently delivers the active ingredient Itaconic acid to skin tissue following oral administration. Itaconic acid prodrug-1 possesses immunomodulatory properties, significantly inhibiting Poly (I:C) /IFNγ-induced inflammatory cytokines in human epidermal keratinocytes. Itaconic acid prodrug-1 can be utilized for the research of alopecia areata and other inflammatory skin diseases[1].
Product Specifications
CAS Number
2641132-66-1
UNSPSC
12352211
Target
Interleukin Related
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
C=C(C(OCOC(OC(C)C)=O)=O)CC(OCOC(OC(C)C)=O)=O
Molecular Formula
C15H22O10
Molecular Weight
362.33
References & Citations
[1]Lee C B, et al. Discovery of Orally Available Prodrugs of Itaconate and Derivatives[J]. Journal of Medicinal Chemistry, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF647 conjugate, 0.1mg/mL
CD106 / VCAM1 (1.4C3), CF488A conjugate, 0.1mg/mL
