LSQ-28
LSQ-28 is an orally active HDAC3 inhibitor with an IC50 of 42 nM, and exhibits potent anticancer, antiproliferative, antimigratory, anti-invasive, and antiwound healing activities. LSQ-28 can be utilized in cancer research[1].
Product Specifications
UNSPSC
12352005
Target
HDAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
CCCNNC(C1=CC=C(CN2C3=C(C4=CC=CC=C24)C(C5=CC=CC=N5)=NC6=C3C=CC=C6)C=C1)=O
Molecular Formula
C31H27N5O
Molecular Weight
485.58
References & Citations
[1]Li S, et al. Discovery of Highly Potent and Orally Bioavailable Histone Deacetylase 3 Inhibitors as Immunomodulators and Enhancers of DNA-Damage Response in Cancer Therapy. J Med Chem. 2025 Jan 28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC3
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6321791-01 0.2 mL
MOSC2, CT (MARC2, MOSC2, MOSC domain-containing protein 2, mitochondrial, Mitochondrial amidoxime reducing component 2, Moco sulfurase C-terminal domain-containing protein 2, Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (APC)
Sign In for Pricing
View Details MBS6321791-02 5x 0.2 mL
MOSC2, CT (MARC2, MOSC2, MOSC domain-containing protein 2, mitochondrial, Mitochondrial amidoxime reducing component 2, Moco sulfurase C-terminal domain-containing protein 2, Molybdenum cofactor sulfurase C-terminal domain-containing protein 2) (APC)
Sign In for Pricing
View Details 
MBS2580293-01 0.02 mg
Recombinant Human NOS2/INOS Protein (Trx Tag)
Sign In for Pricing
View Details