MurA-IN-5
MurA-IN-5 (compound 4c) exhibits (MIC) = 1.95 μg/mL against Escherichia coli and demonstrating significant potency as a MurA inhibitor with (IC50) of 3.77 μg/mL. MurA-IN-5 displays an antibiofilm activity against multiple microorganisms, indicating its potential to combat biofilm-related infections[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
NC1=NN2C(C3=CC=C(C)C=C3)=CC(C4=CC=C(OCC5=CC=CC=C5)C=C4)=NC2=C1/N=N/C6=CC=C(OC)C=C6
Molecular Formula
C33H28N6O2
Molecular Weight
540.61
References & Citations
[1]Omkulthom Al Kamaly, et al. Insights into Novel Arylazopyrazolo[1,5-a]pyrimidines as Promising MurA Inhibitors and Antibiofilm Candidates: Design, Synthesis, Antimicrobial Evaluation, and Molecular Docking. ACS Omega. 2025 Jan 24;10 (4) :4044-4056.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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