HDAC6-IN-52
HDAC6-IN-52 (EX.1) is a potent inhibitor of HDAC6, with the inhibitory rate of 100% at 10 μM. HDAC6-IN-52 plays an important role in central nervous system diseases including neurodegenerative diseases such as Alzheimer’s disease andprogressive supranuclear palsy[1].
Product Specifications
CAS Number
[2636786-68-8]
UNSPSC
12352005
Target
HDAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Neurological Disease
Smiles
O=C1C2=CC(C3=NN=C(O3)C(F)F)=CC=C2CN1[C@@H]([C@H](C4=CC=CC=N4)O)C5=NC=CC=C5
Molecular Formula
C23H17F2N5O3
Molecular Weight
449.41
References & Citations
[1]Ahmed F. Abdel-Magid. Potential of Histone Deacetylase 6 Inhibitors as a Treatment of Neurodegenerative Diseases. ACS Medicinal Chemistry Letters January 25, 2025
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC6
Curated Selection
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