NUAK1-IN-1
NUAK1-IN-1 (Compound 9) is a NUAK1 (IC50 of 5.012 nM) and CDK4 inhibitor. NUAK1-IN-1 can be used in cancer, neurodevelopmental disorders and Alzheimer's disease research[1].
Product Specifications
UNSPSC
12352005
Target
AMPK; CDK
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; PI3K/Akt/mTOR
Field of Research
Cancer; Neurological Disease
Smiles
CC1=CC(N(C2=C1C=NC(NC3=CC=C(C=C3)N4CC5CC(N5C)C4)=N2)C6CCCC6)=O
Molecular Formula
C25H30N6O
Molecular Weight
430.55
References & Citations
[1]Rooney TPC, et al. Development of the Pyrido[2,3-d]pyrimidin-7 (8H) -one Scaffold toward Potent and Selective NUAK1 Inhibitors. ACS Med Chem Lett. 2025 Jan 25;16 (2) :327-335.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK4
Frequently Asked Questions
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