FXR/HSD17B13 modulator 1
FXR/HSD17B13 modulator 1 (compound 6) is a potent modulator of FXR/HSD17B13. FXR/HSD17B13 modulator 1 plays an important roel in metabolic dysfunction-associated steatohepatitis (MASH) research[1].
Product Specifications
CAS Number
3067566-36-0
UNSPSC
12352005
Target
17β-HSD; FXR
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Purity
96.64
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)C1=CC=C(C=C1)C2=CC=C(C=C2)OCC3=C(ON=C3C4=C(C=CC=C4Cl)Cl)C5CC5
Molecular Formula
C26H19Cl2NO4
Molecular Weight
480.34
References & Citations
[1]Shixuan Jiao, et al. Discovery of First-in-Class FXR and HSD17B13 Dual Modulator for the Treatment of Metabolic Dysfunction-Associated Fatty Liver Disease. J Med Chem. 2025 Jan 24.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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