NMDA agonist 2
NMDA agonist 2 (compound 8d) is a potent agonist of NMDA receptor, with the EC50 of 0.034 μM for GluN1/2C. NMDA agonist 2 plays an important role in neurological and psychiatric disorders[1].
Product Specifications
UNSPSC
12352005
Target
IGluR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C([C@@H](CNC(C1=CC(Br)=C(S1)C2=CC=CC=C2F)=O)N)O
Molecular Formula
C14H12BrFN2O3S
Molecular Weight
387.22
References & Citations
[1]Fabao Zhao, et al. Design of (R) -3- (5-Thienyl) carboxamido-2-aminopropanoic Acid Derivatives as Novel NMDA Receptor Glycine Site Agonists: Variation in Molecular Geometry to Improve Potency and Augment GluN2 Subunit-Specific Activity. J Med Chem. 2025 Jan 23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LKU604101 96 Tests
Retinoid X Receptor Alpha (RXRa) Magnetic Luminex Assay Kit
Sign In for Pricing
View Details 
PM53033I1 100 µg
Peroxiredoxin 2 Protein, Mouse, Recombinant (His Tag)
Sign In for Pricing
View Details OPCA00417-100UG 100 µg
Recombinant human Ubiquitin-like protein FUBI
Sign In for Pricing
View Details