GPR119 agonist 3
GPR119 agonist 3 (Compound 21b) is an orally active agonist of GPR119 with an EC50 value of 3.8 nM for hGPR119. Additionally, GPR119 agonist 3 exhibits hypoglycemic effects and can be used in research on type 2 diabetes and obesity[1].
Product Specifications
CAS Number
[2097502-14-0]
UNSPSC
12352005
Target
GPR119
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
CCC1=CN=C(N=C1)N2CCC(CC2)COC3=CC=C(C=C3)C4=CC[C@@H](CC4)C(N5CCC[C@@H]5CO)=O
Molecular Formula
C30H40N4O3
Molecular Weight
504.66
References & Citations
[1]La H, et al. Discovery of 1, 4-Disubstituted Cyclohexene Analogues as Selective GPR119 Agonists for the Treatment of Type 2 Diabetes[J]. Journal of Medicinal Chemistry, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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