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GPR119 agonist 3

GPR119 agonist 3 (Compound 21b) is an orally active agonist of GPR119 with an EC50 value of 3.8 nM for hGPR119. Additionally, GPR119 agonist 3 exhibits hypoglycemic effects and can be used in research on type 2 diabetes and obesity[1].

Product Specifications

CAS Number

2097502-14-0

UNSPSC

12352005

Target

GPR119

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Metabolic Disease

Smiles

CCC1=CN=C(N=C1)N2CCC(CC2)COC3=CC=C(C=C3)C4=CC[C@@H](CC4)C(N5CCC[C@@H]5CO)=O

Molecular Formula

C30H40N4O3

Molecular Weight

504.66

References & Citations

[1]La H, et al. Discovery of 1, 4-Disubstituted Cyclohexene Analogues as Selective GPR119 Agonists for the Treatment of Type 2 Diabetes[J]. Journal of Medicinal Chemistry, 2025.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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