Mitochondria modulator-2
Mitochondria modulator-2 (Compound Ir1) induces the depolarization of mitochondrial membrane potential, induces ROS generation, inhibits cell migration of A549, arrests the cell cycle at G2/M phase, and induces apoptosis in A549[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Mitochondrial Metabolism; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
[F-][P+5]([F-])([F-])([F-])([F-])[F-].[F-][P+5]([F-])([F-])([F-])([F-])[F-].C1(C=CC=C2)=C2[Ir+]34([N]5=C6C7=[N]3C=CC=C7C8=C(NC(C9=CC=C(OCCCC[P+](C%10=CC=CC=C%10)(C%11=CC=CC=C%11)C%12=CC=CC=C%12)C=C9)=N8)C6=CC=C5)(C%13=C(C=CC=C%13)C%14=[N]4C=CC=C%14)[N]%15=CC=CC=C1%15
Molecular Formula
C63H50F12IrN6OP3
Molecular Weight
1420.23
References & Citations
[1]Fu H, et al., Triphenylphosphine-modified cyclometalated iridiumIII complexes as mitochondria-targeting anticancer agents with enhanced selectivity. Bioorg Chem. 2025 Feb;155:108148.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
364119 200 µL
MFAP2 (Microfibrillar Associated Protein 2, MAGP1, Microfibril-associated glycoprotein 1)
Sign In for Pricing
View Details