Apoptosis inducer 35
Apoptosis inducer 35 (Compound 6) is a multi-targeted inhibitor, that reduces the expressions of EGFR, AKT, ERK and P38-MAPKα. Apoptosis inducer 35 inhibits the proliferation of cancer cell A549 and Jurkat, arrests the cell cycle at S phase, and induces apoptosis[1].
Product Specifications
UNSPSC
12352005
Target
Akt; Apoptosis; EGFR; ERK; p38 MAPK
Related Pathways
Apoptosis; JAK/STAT Signaling; MAPK/ERK Pathway; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Cancer
Smiles
CCOC(CSC1=NN=C(CSC2=NN=C(C3=CC4=C(C=CC=C4)N3)N2N)N1C5=CC=C(Cl)C=C5)=O
Molecular Formula
C23H21ClN8O2S2
Molecular Weight
541.05
References & Citations
[1]Boraei ATA, et al., Synthesis of new functionalized bioactive S-substituted indolyl-triazoles as cytotoxic and apoptotic agents through multi-targeted kinase inhibition. Bioorg Chem. 2025 Jan 10;156:108154.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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