HCAI/II-IN-10

HCAI/II-IN-10 (Compound 5d) is a human carbonic anhydrase I and II (hCA I and hCA II) inhibitor with IC50 values are 4.32 and 3.89 nM respectively[1].

Product Specifications

UNSPSC

12352211

Target

Carbonic Anhydrase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Smiles

O=S(C1=CC=C2C(C=CC=C2)=C1)(OC3=C(C=CC=C3)/C=N\NC(NC4=C(C=CC=C4Cl)Cl)=S)=O

Molecular Formula

C24H17Cl2N3O3S2

Molecular Weight

530.45

References & Citations

[1]Eshal J, et al. Synthesis, biological evaluation, and in silico studies of phenyl naphthalene-2-sulfonate derived thiosemicarbazones as potential carbonic anhydrase inhibitors. Bioorg Chem. 2025 Jan 3;155:108118.