AChE/MAO-B-IN-7

AChE/MAO-B-IN-7 (VAV-8) is a blood-brain permeable dual inhibitor of acetylcholinesterase (AchE) and MAO-B agent. AChE/MAO-B-IN-7 can also inhibit Aβ42 aggregation for use in Alzheimer's disease (AD) research[1].

Product Specifications

UNSPSC

12352005

Target

Amyloid-β; Cholinesterase (ChE) ; Monoamine Oxidase

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Smiles

C#CCOC1=CC=C(C=C1OC)C2=NC3=CC=CC=C3C(N4CCOCC4)=N2

Molecular Formula

C22H21N3O3

Molecular Weight

375.42

References & Citations

[1]Kumar V, et al. In vitro and in vivo Investigations of 4-Substituted 2-Phenylquinazoline derivatives as multipotent ligands for the treatment of Alzheimer's disease. Bioorg Chem. 2025 Jan 3;155:108126.