CpNMT-IN-1
CpNMT-IN-1 (Compound 11e) is an against N-myristoyltransferase of C. parvum (CpNMT) inhibitor with an IC50 value of 2.5 μM. CpNMT-IN-1 also inhibits the growth of C. parvum with anEC50[1].
Product Specifications
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
CN1CCN(C1=O)C2=C(C=CC=C2)NC(C3=CC(S(=O)(N(C4=CC=CC=C4)CC)=O)=CC=C3Cl)=O
Molecular Formula
C25H25ClN4O4S
Molecular Weight
513.01
References & Citations
[1]Sigalapalli D K, et al. Structure guided modification of 2-chloro-5- (ethyl-phenyl-sulfamoyl) -N-[2- (2-oxo-pyrrolidin-1-yl) -phenyl]-benzamide to afford selective inhibitors of Cryptosporidium parvum N-myristoyltransferase. Bioorganic & Medicinal Chemistry Letters, 2025: 130092.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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