CpNMT-IN-1

CpNMT-IN-1 (Compound 11e) is an against N-myristoyltransferase of C. parvum (CpNMT) inhibitor with an IC50 value of 2.5 μM. CpNMT-IN-1 also inhibits the growth of C. parvum with anEC50[1].

Product Specifications

UNSPSC

12352005

Target

Parasite

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

CN1CCN(C1=O)C2=C(C=CC=C2)NC(C3=CC(S(=O)(N(C4=CC=CC=C4)CC)=O)=CC=C3Cl)=O

Molecular Formula

C25H25ClN4O4S

Molecular Weight

513.01

References & Citations

[1]Sigalapalli D K, et al. Structure guided modification of 2-chloro-5- (ethyl-phenyl-sulfamoyl) -N-[2- (2-oxo-pyrrolidin-1-yl) -phenyl]-benzamide to afford selective inhibitors of Cryptosporidium parvum N-myristoyltransferase. Bioorganic & Medicinal Chemistry Letters, 2025: 130092.