BRD4 Inhibitor-39
BRD4 Inhibitor-39 (compound 12m) is an orally available BRD4 inhibitor with an IC50 value of 0.02 μM. BRD4 Inhibitor-39 induces apoptosis. BRD4 Inhibitor-39 has anti-tumor activity[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; Epigenetic Reader Domain
Related Pathways
Apoptosis; Epigenetics
Field of Research
Cancer
Smiles
FC1=CC(Br)=C(C=C1)NC2=C(N=C3N2C=C(N=C3)C4=CN(N=C4)C)C(C=C5)=CN6C5=NN=C6CC
Molecular Formula
C24H19BrFN9
Molecular Weight
532.37
References & Citations
[1]Liu JY, et al. Design, synthesis, and antitumor evaluation of triazolopyridine derivatives as novel inhibitors for BRD4. Eur J Med Chem. 2025 Jan 13;285:117272.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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