HIV-1 inhibitor-80
HIV-1 inhibitor-80 (compound M44) is an HIV-1 inhibitor with an EC50 of 5-148 nM. HIV-1 inhibitor-80 shows good metabolic stability and cytotoxicity in human plasma and human liver microsomes[1].
Product Specifications
UNSPSC
12352005
Target
HIV
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
COC1=C(/C(C2=CC=NC(NC3=CC=C(C#N)C=C3)=N2)=N\N)C=CC(C4=CC=C(C#N)C=C4)=C1
Molecular Formula
C26H19N7O
Molecular Weight
445.48
References & Citations
[1]Xiao-Mei Chen, et al. Structure-based discovery of novel diarylpyrimidines as potent and selective Non-Nucleoside reverse transcriptase inhibitors: From CH (CN) -Biphenyl-Diarylpyrimidines to CNNH2-Biphenyl-Diarylpyrimidines. Eur J Med Chem. 2025 Jan 12:285:117271.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
Frequently Asked Questions
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