Rf470 (TFA)
Rf470 (Rotor NO.4) TFA is a FMR-probe-D-lysine conjugate (Max Ex: 470 nM; Max Em: 640 nM) that can be covalently incorporated into peptidoglycan by bacteria. Rf470 TFA has extremely weak fluorescence in the free state, but its fluorescence is significantly enhanced when it is catalytically incorporated into peptidoglycan by transpeptidases. Through fluorescence changes, Rf470 TFA can be used for real-time monitoring of peptidoglycan biosynthesis, detection of transpeptidase activity, and screening of antibiotics, etc[1].
Product Specifications
CAS Number
[2369899-34-1]
Product Name Alternative
Rotor NO.4 (TFA)
UNSPSC
12352211
Target
Bacterial; Fluorescent Dye
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Purity
95.55
Smiles
OC(C(F)(F)F)=O.OC([C@H](N)CCCCNC(CCN1C2=CC=C(C3=CC=C(/C=C(C#N)/C(O)=O)S3)C=C2CCC1)=O)=O
Molecular Formula
C28H31F3N4O7S
Molecular Weight
624.63
References & Citations
[1]Michael VanNIEUWENHZE, et al. Molecular rotor-based d-amino acids as tools for imaging peptidoglycan biosynthesis. WO2019157233A1. 2019-08-15.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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