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RIPK3-IN-6

RIPK3-IN-6 (compound 1) is a type I RIPK3 inhibitor with poor selectivity for the RIPK family, especially for RIPK2 activity[1].

Product Specifications

CAS Number

955879-75-1

UNSPSC

12352203

Target

RIP kinase

Related Pathways

Apoptosis

Field of Research

Cancer

Purity

98.03

Solubility

DMSO : 31.25 mg/mL (ultrasonic)

Smiles

OC1=CC=C(C)C(NC2=CC=NC3=CC(C4=NC=CC=C4)=CC=C23)=C1

Molecular Formula

C21H17N3O

Molecular Weight

327.38

References & Citations

[1]Rodriguez DA, et al. Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis. Cell Death Differ. 2016 Jan;23 (1) :76-88.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

RIPK3

Available Sizes

Frequently Asked Questions

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