514O6,10
514O6,10 is an ionizable lipidoid containing a branched-tail. 514O6,10 can be used to synthesize lipid nanoparticles (LNPs) for delivering mRNA to natural killer and dendritic cells within the lung. 514O6,10 can be used for the RNA therapies for lung diseases associated with immune cell dysregulation, including cancer, viral infections, and autoimmune disorders research[1].
Product Specifications
CAS Number
2863553-06-2
UNSPSC
12352211
Target
Liposome
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Infection; Inflammation/Immunology
Smiles
O=C(CCN(CCN(CCCN(CCN(CCC(OCC(CCCCCCCC)CCCCCC)=O)CCC(OCC(CCCCCCCC)CCCCCC)=O)CC)CC)CCC(OCC(CCCCCCCC)CCCCCC)=O)OCC(CCCCCCCC)CCCCCC
Molecular Formula
C87H172N4O8
Molecular Weight
1402.32
References & Citations
[1]Petersen DMS, et al. Branched-Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice. Adv Healthc Mater. 2024 Sep;13 (22) :e2400225.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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