514O6,10

514O6,10 is an ionizable lipidoid containing a branched-tail. 514O6,10 can be used to synthesize lipid nanoparticles (LNPs) for delivering mRNA to natural killer and dendritic cells within the lung. 514O6,10 can be used for the RNA therapies for lung diseases associated with immune cell dysregulation, including cancer, viral infections, and autoimmune disorders research[1].

Product Specifications

CAS Number

[2863553-06-2]

UNSPSC

12352211

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer; Infection; Inflammation/Immunology

Smiles

O=C(CCN(CCN(CCCN(CCN(CCC(OCC(CCCCCCCC)CCCCCC)=O)CCC(OCC(CCCCCCCC)CCCCCC)=O)CC)CC)CCC(OCC(CCCCCCCC)CCCCCC)=O)OCC(CCCCCCCC)CCCCCC

Molecular Formula

C87H172N4O8

Molecular Weight

1402.32

References & Citations

[1]Petersen DMS, et al. Branched-Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice. Adv Healthc Mater. 2024 Sep;13 (22) :e2400225.