RSV-IN-13

RSV-IN-13 (compound 24) is a selective RSV fusion protein inhibitor with antiviral activity. RSV-IN-13 has an EC50 of 444.2 nM against RSV A2 strain and a CC90 of 23.7 μM in HepG2 cells. RSV-IN-13 can block the virus from entering host cells. RSV-IN-13 can be used to study RSV infection[1].

Product Specifications

CAS Number

[2724259-07-6]

UNSPSC

12352005

Target

RSV

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

N#CC1=CC(N=C(CN2C(C3(CC3)C4=CC=C(C=C42)F)=O)N5CCCC(F)(F)F)=C5C=C1

Molecular Formula

C23H18F4N4O

Molecular Weight

442.41

References & Citations

[1]Cockerill GS, et al. Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion. J Med Chem. 2021 Apr 8;64 (7) :3658-3676.