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THP1 Lipid

THP1 Lipid is an ionizable lipidoid. THP1 Lipid can be used to synthesize lipid nanoparticles (LNPs) for delivering mRNA to muscles with minimal toxicity and editing genes in specific liver tissues in tdTomato transgenic mice model. THP1 Lipid can be used for vaccine delivery and CRISPR/Cas9-mediated gene editing research[1].

Product Specifications

CAS Number

3097638-13-3

UNSPSC

12352005

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Smiles

O=C(C1=C(N(CN(C1)CCCCCCCC)CCCCCCCC)C(OCC)=O)OCC

Molecular Formula

C26H48N2O4

Molecular Weight

452.67

References & Citations

[1]Isaac I, et al. Tetrahydropyrimidine Ionizable Lipids for Efficient mRNA Delivery. ACS Nano. 2024 Oct 22;18 (42) :29045-29058.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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