Tri (GalNAc-PEG2) -PEG4-cyclo (Ac-DCAW-{Arg (3F-Ph) -PEG2}-LGELVWCT) (Cys2-Cys12)
Selected Variant
HY-171910-01
Size: 500 µg
Tri (GalNAc-PEG2) -PEG4-cyclo (Ac-DCAW-{Arg (3F-Ph) -PEG2}-LGELVWCT) (Cys2-Cys12) is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research[1].
Product Specifications
UNSPSC
12352203
Target
Asialoglycoprotein Receptor (ASGPR) ; LYTACs
Related Pathways
Immunology/Inflammation; PROTAC
Field of Research
Others
Purity
99.46
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N1)=O)C(C)C)=O)CC(C)C)=O)CCC(O)=O)=O)=O)CC(C)C)=O)CC(NCC2=CC(F)=C(C=C2)OC(CCOCCOCCNC(CCOCCOCCOCCOCCC(NCC(NC(COCCC(NCCOCCOCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)NC(C)=O)=O)(COCCC(NCCOCCOCCO[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O)NC(C)=O)=O)COCCC(NCCOCCOCCO[C@H]5[C@@H]([C@H]([C@H]([C@H](O5)CO)O)O)NC(C)=O)=O)=O)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)C)=O)NC([C@@H](NC(C)=O)CC(O)=O)=O)C(N[C@H](C(O)=O)[C@H](O)C)=O)[C@@H]1CC8=CNC9=CC=CC=C89
Molecular Formula
C152H236FN25O62S2
Molecular Weight
3488.76
References & Citations
[1]Dubowchik G M, et al. Bifunctional degraders of galactose-deficient immunoglobulins. WO2024228935A1. 2024-11-07.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Price
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