Glycerophosphoinositol 4,5-diphosphate (trisodium)
Glycerophosphoinositol 4,5-diphosphate (GroPI (4,5) P2) trisodium is a slowly metabolized analog of InsP3. Glycerophosphoinositol 4,5-diphosphate trisodium has an EC50 of 1.228 μM for inducing calcium release, with a degradation time constant of 13 seconds. Glycerophosphoinositol 4,5-diphosphate trisodium can be used to study the effect of InsP3 degradation on calcium signal recovery[1].
Product Specifications
Product Name Alternative
GroPI (4,5) P2 (trisodium) ; GPIP2 (trisodium)
UNSPSC
12352128
Target
Calcium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Others
Smiles
O[C@@H]1[C@H]([C@@H]([C@H]([C@@H]([C@@H]1O)OP(OC[C@@H](CO)O)(O[Na])=O)O)OP(O)(O[Na])=O)OP(O)(O[Na])=O
Molecular Formula
C9H18Na3O17P3
Molecular Weight
560.12
References & Citations
[1]Fink CC, et al. Determination of time-dependent inositol-1,4,5-trisphosphate concentrations during calcium release in a smooth muscle cell. Biophys J. 1999 Jul;77 (1) :617-28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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