Glycerophosphoinositol 4,5-diphosphate (trisodium)

Glycerophosphoinositol 4,5-diphosphate (GroPI (4,5) P2) trisodium is a slowly metabolized analog of InsP3. Glycerophosphoinositol 4,5-diphosphate trisodium has an EC50 of 1.228 μM for inducing calcium release, with a degradation time constant of 13 seconds. Glycerophosphoinositol 4,5-diphosphate trisodium can be used to study the effect of InsP3 degradation on calcium signal recovery[1].

Product Specifications

Product Name Alternative

GroPI (4,5) P2 (trisodium) ; GPIP2 (trisodium)

UNSPSC

12352128

Target

Calcium Channel

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Others

Smiles

O[C@@H]1[C@H]([C@@H]([C@H]([C@@H]([C@@H]1O)OP(OC[C@@H](CO)O)(O[Na])=O)O)OP(O)(O[Na])=O)OP(O)(O[Na])=O

Molecular Formula

C9H18Na3O17P3

Molecular Weight

560.12

References & Citations

[1]Fink CC, et al. Determination of time-dependent inositol-1,4,5-trisphosphate concentrations during calcium release in a smooth muscle cell. Biophys J. 1999 Jul;77 (1) :617-28.