A28-C6B2
A28-C6B2 is an ionizable cationic lipid with a pKa of 6.43, and can be used to generate lipid nanoparticles (LNPs) for mRNA delivery in vivo. A28-C6B2 can be studied in research for enhancing the selective delivery of mRNA to the spleen, particularly to antigen-presenting cells[1].
Product Specifications
UNSPSC
12352211
Target
Liposome
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Smiles
OCCCCCN(CCCCCC(OCC(CCCC)CCCCCC)=O)CCCCCC(OCC(CCCC)CCCCCC)=O
Molecular Formula
C41H81NO5
Molecular Weight
668.09
References & Citations
[1]Ren, Y., et al., (2024) . Enhancing spleen-targeted mRNA delivery with branched biodegradable tails in lipid nanoparticles. Journal of materials chemistry. B, 12 (33), 8062–8066.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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