CRBN ligand-185

CRBN ligand-185 is a CRBN ligand. CRBN ligand-185 can be used as a target protein ligand for the synthesis of PROTACs targeting CRBN (Ligands for Target Protein for PROTAC), such as NX-5948 (HY-153321) [1].

Product Specifications

UNSPSC

12352005

Target

Btk; Ligands for Target Protein for PROTAC

Related Pathways

PROTAC; Protein Tyrosine Kinase/RTK

Field of Research

Cancer; Inflammation/Immunology

Smiles

O=C(NC(CC1)=O)[C@H]1NC(C2=NC=CC=C2)=O

Molecular Formula

C11H11N3O3

Molecular Weight

233.22

References & Citations

[1]Mark Noviski, et al. NX-5948, a Selective Degrader of BTK, Significantly Reduces Inflammation in a Model of Autoimmune Disease. 2021 Nurix Therapeutics, Inc.