CRBN ligand-185
CRBN ligand-185 is a CRBN ligand. CRBN ligand-185 can be used as a target protein ligand for the synthesis of PROTACs targeting CRBN (Ligands for Target Protein for PROTAC), such as NX-5948.
Product Specifications
UNSPSC
12352005
Target
Btk; Ligands for Target Protein for PROTAC
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C(NC(CC1)=O)[C@H]1NC(C2=NC=CC=C2)=O
Molecular Formula
C11H11N3O3
Molecular Weight
233.22
References & Citations
[1]Mark Noviski, et al. NX-5948, a Selective Degrader of BTK, Significantly Reduces Inflammation in a Model of Autoimmune Disease. 2021 Nurix Therapeutics, Inc.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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