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Nef ligand-1

Nef ligand-1 is the Nef binding part of FC-14367 (HY-171859) [1].

Product Specifications

CAS Number

[2416170-64-2]

UNSPSC

12352005

Target

HIV

Related Pathways

Anti-infection

Field of Research

Cancer

Smiles

FC1=CC=C(CCC2=C(N(C3=NC4=C(N3)C=CC(Cl)=C4)N=C2C5CCNCC5)O)C=C1

Molecular Formula

C23H23ClFN5O

Molecular Weight

439.91

References & Citations

[1]Emert-Sedlak LA, et al. PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication. Cell Chem Biol. 2024 Apr 18;31 (4) :658-668.e14.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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