Nef ligand-1
Nef ligand-1 is the Nef binding part of FC-14367 (HY-171859) [1].
Product Specifications
CAS Number
[2416170-64-2]
UNSPSC
12352005
Target
HIV
Related Pathways
Anti-infection
Field of Research
Cancer
Smiles
FC1=CC=C(CCC2=C(N(C3=NC4=C(N3)C=CC(Cl)=C4)N=C2C5CCNCC5)O)C=C1
Molecular Formula
C23H23ClFN5O
Molecular Weight
439.91
References & Citations
[1]Emert-Sedlak LA, et al. PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication. Cell Chem Biol. 2024 Apr 18;31 (4) :658-668.e14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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