Iodoquine

Iodoquine is an analog of chloroquine. Iodoquine exhibits high uptake in tumor cells and can localize to cells with high ALDH1 content, including cancer stem cells. With low uptake in normal brain tissue, iodoquine can be used in research related to tumor diagnosis or as a radiotracer[1][2].

Product Specifications

CAS Number

[2007-00-3]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Cancer

Smiles

IC1=CC2=NC=CC(NC(CCCN(CC)CC)C)=C2C=C1

Molecular Formula

C18H26IN3

Molecular Weight

411.32

References & Citations

[1]Chin BB, et al. Synthesis and preliminary evaluation of n.c.a. iodoquine: a novel radiotracer with high uptake in cells with high ALDH1 expression. Curr Radiopharm. 2012 Jan;5 (1) :47-58.|[2]Chin B, et al. Iodoquine as a potential PET radiolabel for in vivo cell trafficking of leukocyte tumor cell lines. 2012.