GLP-1R modulator-1
GLP-1R modulator-1 (Compound 384) is an orally active, potent selective glucagon-like peptide-1 receptor (GLP-1R) agonist. GLP-1R modulator-1 activates G-protein coupled signaling, elevates intracellular cAMP levels, promotes insulin secretion, delays gastric emptying and suppresses appetite. GLP-1R modulator-1 is promising for research of type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH) [1].
Product Specifications
CAS Number
[2978244-71-0]
UNSPSC
12352005
Target
GLP Receptor
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease; Inflammation/Immunology
Smiles
C[C@@]1(C2=C(C=C(C=C2)Cl)F)OC3=C(C4=CCN(CC5=NC6=CC(NC(C7=CC(C)=C(NN=C8C)C8=C7)=O)=CC=C6N5C[C@@H]9CCO9)CC4)C=CC=C3O1
Molecular Formula
C41H38ClFN6O4
Molecular Weight
733.23
References & Citations
[1]Bin Liang, et al. Glp-1r modulating compounds. US20230271949A1. 2023-08-31.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-171850/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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