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T9, t11, c15-CLNA

T9, t11, c15-CLNA is a conjugated linolenic acid (CLNA) isomer produced by Lactobacillus plantarum ZS2058. t9, t11, c15-CLNA has the main activities of anti-inflammatory, antioxidant and improving intestinal barrier function. The regulatory mechanism of t9, t11, c15-CLNA includes upregulation of tight junction proteins, inhibition of pro-inflammatory cytokines (such as TNF-α, IL-6) and activation of antioxidant enzymes (such as SOD, CAT) . t9, t11, c15-CLNA can be used in the study of inflammatory bowel diseases (such as colitis) [1].

Product Specifications

CAS Number

[678138-44-8]

UNSPSC

12352211

Target

Interleukin Related; SOD; TNF Receptor

Related Pathways

Apoptosis; Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

CC/C=C\CC/C=C/C=C/CCCCCCCC(O)=O

Molecular Formula

C18H30O2

Molecular Weight

278.43

References & Citations

[1]Ren Q, et al. c9, t11, c15-CLNA and t9, t11, c15-CLNA from Lactobacillus plantarum ZS2058 Ameliorate Dextran Sodium Sulfate-Induced Colitis in Mice. J Agric Food Chem. 2020 Mar 25;68 (12) :3758-3769.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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