C9, t11, c15-CLNA
C9, t11, c15-CLNA is a conjugated linolenic acid (CLNA) isomer produced by Lactobacillus plantarum ZS2058. c9, t11, c15-CLNA has significant anti-proliferation activity against colon cancer cells (IC50: 18.26 μM) . c9, t11, c15-CLNA induces pyroptosis by activating the canonical pyroptosis pathway mediated by caspase-1. c9, t11, c15-CLNA can be used in the study of colon cancer[1].
Product Specifications
CAS Number
[15909-18-9]
UNSPSC
12352211
Target
Caspase
Related Pathways
Apoptosis
Field of Research
Cancer
Smiles
CC/C=C\CC/C=C/C=C\CCCCCCCC(O)=O
Molecular Formula
C18H30O2
Molecular Weight
278.43
References & Citations
[1]Ren Q, et al. Antiproliferation Activity and Mechanism of c9, t11, c15-CLNA and t9, t11, c15-CLNA from Lactobacillus plantarum ZS2058 on Colon Cancer Cells. Molecules. 2020 Mar 9;25 (5) :1225.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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