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C9, t11, c15-CLNA

C9, t11, c15-CLNA is a conjugated linolenic acid (CLNA) isomer produced by Lactobacillus plantarum ZS2058. c9, t11, c15-CLNA has significant anti-proliferation activity against colon cancer cells (IC50: 18.26 μM) . c9, t11, c15-CLNA induces pyroptosis by activating the canonical pyroptosis pathway mediated by caspase-1. c9, t11, c15-CLNA can be used in the study of colon cancer[1].

Product Specifications

CAS Number

15909-18-9

UNSPSC

12352211

Target

Caspase

Related Pathways

Apoptosis

Field of Research

Cancer

Smiles

CC/C=C\CC/C=C/C=C\CCCCCCCC(O)=O

Molecular Formula

C18H30O2

Molecular Weight

278.43

References & Citations

[1]Ren Q, et al. Antiproliferation Activity and Mechanism of c9, t11, c15-CLNA and t9, t11, c15-CLNA from Lactobacillus plantarum ZS2058 on Colon Cancer Cells. Molecules. 2020 Mar 9;25 (5) :1225.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Frequently Asked Questions

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