Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide) -NMT-IN-7

Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide) -NMT-IN-7 (Compound DC-2) is a drug-linker conjugate for ADC. Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide) -NMT-IN-7 consists of a NMT inhibitor (HY-160945) and a stable and cleavable linker (Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide) ) . Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide) -NMT-IN-7 can be used for synthesis of ADCs[1].

Product Specifications

CAS Number

[3032302-82-9]

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC; N-myristoyltransferase

Related Pathways

Antibody-drug Conjugate/ADC Related; Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

O=C(C=CC1=O)N1CCOCCOCCC(NCCC(NC(C=C2COC(N(C)CC3=CN=C4N3C=C(C5=C(C(F)=C(C=C5)F)OCCC6=C(C)N(C)N=C6C(O)C(C)(C)C)C=C4)=O)=C(C=C2)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)C(O)=O)=O)=O