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Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide) -NMT-IN-7

Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide) -NMT-IN-7 (Compound DC-2) is a drug-linker conjugate for ADC. Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide) -NMT-IN-7 consists of a NMT inhibitor and a stable and cleavable linker (Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide) ). Mal-PEG2-amide-C2-amide-Phenyl (β-D-glucuronide) -NMT-IN-7 can be used for synthesis of ADCs[1].

Product Specifications

CAS Number

3032302-82-9

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC; N-myristoyltransferase

Related Pathways

Antibody-drug Conjugate/ADC Related; Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

O=C(C=CC1=O)N1CCOCCOCCC(NCCC(NC(C=C2COC(N(C)CC3=CN=C4N3C=C(C5=C(C(F)=C(C=C5)F)OCCC6=C(C)N(C)N=C6C(O)C(C)(C)C)C=C4)=O)=C(C=C2)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)C(O)=O)=O)=O

Molecular Formula

C55H66F2N8O17

Molecular Weight

1149.15

References & Citations

[1]Robin C, et al. Antibody drug conjugate comprising nmt inhibitor and its use. WO2024052684A1. 2024-03-14.

Shipping Conditions

Room temperature

Scientific Category

ADC Related

Clinical Information

No Development Reported

Frequently Asked Questions

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