PSB-0963
PSB-0963 is a selective and competitive ecto-5'-nucleotidase (eN/CD73) inhibitor with a Ki of 150 nM for rat ecto-5'-nucleotidase. PSB-0963 shows high selectivity over other ectonucleotidases (NTPDases 1-3) and P2Y receptors. PSB-0963 can be used for the study of cancer[1].
Product Specifications
CAS Number
[1213268-73-5]
UNSPSC
12352005
Target
CD73
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Smiles
O=C1C2=C(C(C3=C(NC4=CC5=CC6=C(C=CC=C6)C=C5C=C4)C=C(S(=O)(O[Na])=O)C(N)=C13)=O)C=CC=C2
Molecular Formula
C28H17N2NaO5S
Molecular Weight
516.50
References & Citations
[1]Baqi Y, et al. Development of potent and selective inhibitors of ecto-5'-nucleotidase based on an anthraquinone scaffold. J Med Chem. 2010;53 (5) :2076-2086.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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