ASP9831
ASP9831 is an orally active PDE4 inhibitor. ASP9831 inhibits LSP-induced TNF-α production and has anti-inflammatory activity. ASP9831 can be used in fatty liver disease research[1].
Product Specifications
CAS Number
728013-50-1
UNSPSC
12352005
Target
Phosphodiesterase (PDE) ; TNF Receptor
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C(O)CCC1=C(C2=CC(C)=CN=C2)C3=CC=C(CC)N3N=C1COC
Molecular Formula
C20H23N3O3
Molecular Weight
353.41
References & Citations
[1]Ratziu V, et al. Lack of efficacy of an inhibitor of PDE4 in phase 1 and 2 trials of patients with nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2014 Oct;12 (10) :1724-30.e5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE4
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