ASP9831

ASP9831 is an orally active PDE4 inhibitor. ASP9831 inhibits LSP-induced TNF-α production and has anti-inflammatory activity. ASP9831 can be used in fatty liver disease research[1].

Product Specifications

CAS Number

[728013-50-1]

UNSPSC

12352005

Target

Phosphodiesterase (PDE) ; TNF Receptor

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology

Smiles

O=C(O)CCC1=C(C2=CC(C)=CN=C2)C3=CC=C(CC)N3N=C1COC

Molecular Formula

C20H23N3O3

Molecular Weight

353.41

References & Citations

[1]Ratziu V, et al. Lack of efficacy of an inhibitor of PDE4 in phase 1 and 2 trials of patients with nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2014 Oct;12 (10) :1724-30.e5.