CRBN ligand-184
CRBN ligand-184 is a ligand for CRBN-type E3 ubiquitin ligases. CRBN ligand-184 can be used to synthesize PROTAC AU-24118 (HY-163410) [1].
Product Specifications
CAS Number
[2259851-81-3]
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(NC1=O)CCC1OC2=CC=CC=C2
Molecular Formula
C11H11NO3
Molecular Weight
205.21
References & Citations
[1]Tongchen He, et al. Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer. bioRxiv [Preprint]. 2024 Mar 2:2024.02.29.582768.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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