β-Ethoxy-α-ketobutyraldehyde

β-Ethoxy-α-ketobutyraldehyde is a chemical probe. β-Ethoxy-α-ketobutyraldehyde specifically modifies the N1 and N2 positions of guanine. β-Ethoxy-α-ketobutyraldehyde is mainly used to study the steric protection of single-stranded/double-stranded regions of nucleic acids and protein binding sites. β-Ethoxy-α-ketobutyraldehyde can be used for nucleic acid structure analysis and footprint studies of protein-nucleic acid complexes[1].